Recombinant EGFR (Epidermal Growth Factor Receptor) Antibody
Product Sizes
100 ug
£671.00
1956-MSM27-P1ABX-100UG
About this Product
- SKU:
- 1956-MSM27-P1ABX
- Additional Names:
- Proto-oncogene c-ErbB-1 | Receptor tyrosine-protein kinase erbB-1
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- rEGFR/6389
- Clonality:
- Monoclonal
- Extra Details:
- This MAb recognizes a protein of 170kDa; identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1; -2; -3 -4 or HER-1; -2; -3 -4. It binds to Epidermal Growth Factor (EGF); Transforming Growth Factor-a (TGF-a); Heparin-binding EGF (HB-EGF); amphiregulin; betacellulin and epiregulin. EGFR is overexpressed in tumors of breast; brain; bladder; lung; gastric; head & neck; esophagus; cervix; vulva; ovary; and endometrium. It is predominantly present in squamous cell carcinomas.
- Host:
- Mouse
- Immunogen:
- Recombinant extracellular domain of human EGFR; aa25-645
- Isotype:
- IgG2a
- Molecular Weight:
- ~170kDa (wild type) and ~145kDa (vIII variant)
- Research Area:
- AKT Signaling; Bladder Cancer; Breast Cancer; Cardiovascular; Colon Cancer; Developmental Biology; Infectious Disease; MAPK Signaling; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=113196
