E4F1 Antibody
Product Sizes
100 ug
£671.00
1877-MSM1-P1ABX-100UG
About this Product
- SKU:
- 1877-MSM1-P1ABX
- Additional Names:
- E4F transcription factor 1 | Putative E3 ubiquitin-protein ligase E4F1 | RING-type E3 ubiquitin transferase E4F1 | Transcription factor E4F | p120E4F | p50E4F
- Application:
- Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- PCRP-E4F1-2D1
- Clonality:
- Monoclonal
- Extra Details:
- E4F1 (E4F transcription factor 1); also known as E4F; is a 784 amino acid protein that localizes to both the nucleus and the cytoplasm and contains 9 C2H2-type zinc fingers. Expressed ubiquitously in adult and fetal tissues; E4F1 exists as a homodimer that binds DNA and is thought to act as a transcriptional repressor and may also play a role in cell survival and growth via cell cycle control. Additionally; E4F1 is thought to function as a ubiquitin ligase that mediates the ubiquitination (and subsequent degradation) of target proteins and may be involved in the p53 tumor suppressor pathway. E4F1; which may be post-translationally phosphorylated or sumoylated; is subject to proteolytic cleavage which results in the creation of a short peptide with specific DNA binding capabilities.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human E4F1 protein
- Isotype:
- IgG1
- Molecular Weight:
- 83kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=113107
