Recombinant Desmoglein-1 (DSG1) Antibody
Product Sizes
100 ug
£671.00
1828-RBM8-P1ABX-100UG
About this Product
- SKU:
- 1828-RBM8-P1ABX
- Additional Names:
- Cadherin family member 4 | Desmosomal glycoprotein 1 | Pemphigus foliaceus antigen
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- DSG1/8576R
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of ~150kDa; identified as Desmoglein-1 (DSG1). Desmoglein-1 is a member of the desmosomal cadherin family. �Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1; Dsg2; Dsg3; and Dsg4 isoforms. �Within the desmosome; the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins; whereas the intracellular domain is essential for binding to the desmosomal plaque protein; plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity.
- Host:
- Rabbit
- Immunogen:
- Recombinant human DSG1 protein
- Isotype:
- IgG
- Molecular Weight:
- 150kDa (precursor); 160kDa (mature)
- Research Area:
- Developmental Biology; Immunology; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=127463
