Desmoglein-1 (DSG1) Antibody
Product Sizes
100 ug
£671.00
1828-MSM1-P1ABX-100UG
About this Product
- SKU:
- 1828-MSM1-P1ABX
- Additional Names:
- Cadherin family member 4 | Desmosomal glycoprotein 1 | Pemphigus foliaceus antigen
- Application:
- Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- 18D4
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of ~150kDa; identified as Desmoglein-1 (DSG1). Desmoglein-1 is a member of the desmosomal cadherin family.Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1; Dsg2; Dsg3; and Dsg4 isoforms.Within the desmosome; the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins; whereas the intracellular domain is essential for binding to the desmosomal plaque protein; plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity.
- Host:
- Mouse
- Immunogen:
- Human desmoglein-1 intracellular domain
- Isotype:
- IgG1
- Molecular Weight:
- 150kDa (precursor); 160kDa (mature)
- Research Area:
- Autophagy; Developmental Biology; Immunology; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=113015
