DNMT1 / DNA Methyltransferase 1 Antibody
Product Sizes
100 ug
£671.00
1786-MSM1-P1ABX-100UG
About this Product
- SKU:
- 1786-MSM1-P1ABX
- Additional Names:
- CXXC-type zinc finger protein 9 | DNA methyltransferase HsaI | MCMT
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- DNMT1/2061
- Clonality:
- Monoclonal
- Extra Details:
- This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia; deafness; and narcolepsy; and neuropathy; hereditary sensory; type IE.
- Host:
- Mouse
- Immunogen:
- Recombinant human DNMT1 protein fragment (around aa 767-912) (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 184kDa
- Research Area:
- Cardiovascular; Infectious Disease; Nuclear Marker; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=112980
