IDO2 / Indoleamine 2;3-dioxygenase 2 Antibody
Product Sizes
100 ug
£671.00
169355-MSM1-P1-100UG
About this Product
- SKU:
- 169355-MSM1-P1
- Additional Names:
- Indoleamine 2;3-dioxygenase-like protein 1 | Indoleamine-pyrrole 2;3-dioxygenase-like protein 1
- Application:
- ELISA, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- IDO2/2638
- Clonality:
- Monoclonal
- Extra Details:
- IDO2 is a presumptive immunomodulatory gene based on its close structural relationship to IDO1 and its expression in a variety of antigen-presenting cell types. Both IDO1 and IDO2 will catabolize tryptophan to kynurenine. Biochemical studies indicate that both enzymes are similarly robust in catabolic activity; although the in vitro conditions required for IDO2 to manifest the same level of activity differ somewhat from IDO1. However; whether IDO2 is active as a tryptophan catabolizing enzyme in human dendritic cells has been disputed. Further work is needed to conclusively determine that IDO1 and IDO2 are similar in their preference for substrates and reaction pathways to generate product. A non-redundant function for IDO2 relative to IDO1 is suggested by their rather distinct expression patterns and response to extracellular stimuli.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 200-350) of human IDO2 protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 47kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide store at 2 to 8 °C. Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=112894
