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Antibodies

Recombinant Desmin (Muscle Cell Marker) Antibody

Product Sizes
100 ug
£671.00
1674-MSM11-P1-100UG
About this Product
SKU:
1674-MSM11-P1
Application:
Immunohistochemistry
translate.label.attr.clone:
rDES/8846
Clonality:
Monoclonal
Extra Details:
Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain α-helical coiled-coil molecules arranged on an imperfect helical lattice; and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin; a related class III IF; are both expressed during skeletal muscle development. Desmin; a 469 amino acid protein found near the Z line in sarcomeres; is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth; skeletal; and cardiac muscles. �Antibody reacts with leiomyomas; leiomyosarcoma; rhabdomyomas; rhabdomyosarcoma; and perivascular cells of glomus tumors of the skin. �
Host:
Mouse
Immunogen:
Recombinant full-length human desmin protein
Isotype:
IgG1
Molecular Weight:
52kDa
Research Area:
Cardiovascular; Mesenchymal Stem Cell Differentiation
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody