Recombinant Decorin Antibody
Product Sizes
100 ug
£671.00
1634-RBM7-P1ABX-100UG
About this Product
- SKU:
- 1634-RBM7-P1ABX
- Additional Names:
- Bone proteoglycan II | PG-S2 | PG40
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- DCN/8715R
- Clonality:
- Monoclonal
- Extra Details:
- Decorin is a small leucine-rich proteoglycan (SLRP) family member that consists of a glycosaminoglycan chain-containing core protein. The core protein contains ten leucine rich repeats that contain sites for glycosylation; flanked by disulfide bond stabilizing loops. Decorin binds to Collagen Type I; II and IV in vivo and promotes the formation of fibers with variations in stability and solubility. The Decorin core protein binds to growth factors; intercellular matrix molecules; such as Fibronectin and Thrombospondin; and to the Decorin endocytosis receptor. Decorin binds to and inhibits TGFβ and is a direct or indirect negative modulator of TGFβ synthesis. Inhibition of Decorin core protein gene expression by the combination of IFN-γ and TNFα may contribute to cartilage destruction that is characteristic of inflammatory joint diseases. For immunostaining; pre-incubation with chondroitinase-SBC or testicular hyaluronidase may be required to expose the epitope.
- Host:
- Rabbit
- Immunogen:
- Recombinant human Decorin protein fragment (around aa212-336) (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 43kDa
- Research Area:
- Articular Cartilage Extracellular Matrix; Cardiovascular; Complement System; Infectious Disease; Mesenchymal Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=130428
