Drebrin 1 (DBN1) Antibody
Product Sizes
100 ug
£671.00
1627-MSM1-P1ABX-100UG
About this Product
- SKU:
- 1627-MSM1-P1ABX
- Additional Names:
- Developmentally-regulated brain protein
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- DBN1/2879
- Clonality:
- Monoclonal
- Extra Details:
- Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration; extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2); and an adult type (A); generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle; heart; placenta; pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (aa 150-281) of human DBN1 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 120kDa
- Research Area:
- Neuroscience; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=112804
