DAXX (Transcriptional Corepressor) Antibody
Product Sizes
100 ug
£671.00
1616-MSM6-P1ABX-100UG
About this Product
- SKU:
- 1616-MSM6-P1ABX
- Additional Names:
- Daxx | ETS1-associated protein 1 | Fas death domain-associated protein
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry
- translate.label.attr.clone:
- PCRP-DAXX-5G11
- Clonality:
- Monoclonal
- Extra Details:
- This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins; such as apoptosis antigen Fas; centromere protein C; and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus; the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm; the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications; including sumoylation; phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human DAXX protein
- Isotype:
- IgG2b
- Molecular Weight:
- 81.37kDa
- Research Area:
- Apoptosis; Autophagy; Infectious Disease; MAPK Signaling; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=112801
