CD55 / Decay Accelerating Factor (DAF) Antibody

Product Sizes

100 ug

£671.00

1604-MSM4-P1ABX-100UG

About this Product

SKU:: 1604-MSM4-P1ABX
Application:: Western Blot
translate.label.attr.clone:: CD55/6795
Clonality:: Monoclonal
Extra Details:: Recognizes a single chain glycoprotein of 70kDa; identified as CD55/DAF. It is widely expressed on cells throughout the body including leukocytes; erythrocytes; epithelium; endothelium; and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases; C4b2a and C3bBb; and the C5-convertase; C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The MAb 143-30 may be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).
Host:: Mouse
Immunogen:: Recombinant fragment (around aa1-100) of human CD55 (exact sequence is proprietary)
Isotype:: IgG1
Molecular Weight:: 70kDa
Research Area:: B Cell Markers; Complement System; Endothelial Cell Marker; Immunology; Mast Cell Marker; Signal Transduction
Shipping Conditions:: Blue Ice
Storage Conditions:: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:: NeoBiotechnologies
Type:: Antibodies: Monoclonal Antibody

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