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Antibodies

BTLA Antibody

Product Sizes
20 ug
£364.00
151888-MSM1-P0-20UG
About this Product
SKU:
151888-MSM1-P0
Additional Names:
B- and T-lymphocyte-associated protein | CD272
Application:
ELISA
translate.label.attr.clone:
BTLA/1528
Clonality:
Monoclonal
Extra Details:
B and T lymphocyte attenuator (BTLA) is an immunoglobulin domain-containing glycoprotein whose expression is induced during T-cell activation. BTLA is similar to CTLA-4 and PD-1; all of which are coinhibitory receptors belonging to the CD28 family. However; unlike CTLA-4 and PD-1; BTLA does not interact with B7-Ig family counter receptors. Rather; the herpesvirus entry mediator (HVEM); a TNF receptor; acts as a molecular switch that modulates T-cell activation by propagating inhibitory signals through BTLA. The BTLAHVEM interaction is conserved between Mouse and human; suggesting that this system is an important pathway regulating lymphocyte activation.
Host:
Mouse
Immunogen:
Recombinant full-length human BTLA protein
Isotype:
IgG2b
Molecular Weight:
33kDa
Research Area:
B Cell Markers; Dendritic Cell Marker; Immune checkpoint; Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody