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Antibodies

Cathepsin K (Marker of Tumor Invasiveness) Antibody

Product Sizes
100 ug
£671.00
1513-MSM3-P1-100UG
About this Product
SKU:
1513-MSM3-P1
Additional Names:
Cathepsin O | Cathepsin O2 | Cathepsin X
Application:
Immunohistochemistry
translate.label.attr.clone:
CTSK/2793
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein; which is a member of the peptidase C1 protein family; is predominantly expressed in osteoclasts. However; the encoded protein is also expressed in a significant fraction of human breast cancers; where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis; an autosomal recessive disease characterized by osteosclerosis and short stature.
Host:
Mouse
Immunogen:
Recombinant fragment of human Cathepsin K protein (around aa 163-274) (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
39kDa
Research Area:
Cardiovascular; Immunology; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody