Recombinant Cathepsin D (Tumor Marker) Antibody
Product Sizes
100 ug
£671.00
1509-RBM9-P1ABX-100UG
About this Product
- SKU:
- 1509-RBM9-P1ABX
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- CTSD/9613R
- Clonality:
- Monoclonal
- Extra Details:
- Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 52kDa preprocathepsin D that is cleaved and glycosylated to form a 48kDa procathepsin D and then further cleaved to produce 34kDa and 14kDa subunits (heavy and light chains; respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases; including breast cancer and possibly Alzheimer's disease.
- Host:
- Rabbit
- Immunogen:
- His-tagged CTSD protein
- Isotype:
- IgG
- Molecular Weight:
- 48kDa (Procathepsin D); 34kDa (Cathepsin D); 14kDa (Cathepsin D)
- Research Area:
- Apoptosis; Autophagy; Cardiovascular; Immunology; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=136887
