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Antibodies

Catenin; beta (p120) Antibody

Product Sizes
100 ug
£671.00
1499-MSM6-P1ABX-100UG
About this Product
SKU:
1499-MSM6-P1ABX
Additional Names:
Beta-catenin
Application:
Flow Cytometry, Immunofluorescence, Western Blot
translate.label.attr.clone:
9F2
Clonality:
Monoclonal
Extra Details:
This MAb recognizes a protein of 92kDa; which is identified as beta-catenin. It shows no cross-reaction with gamma-catenin (also known as plakoglobin). The catenins; alpha; beta and gamma bind to the highly conserved; intracellular cytoplasmic tail of E-cadherin. Together; the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin was initially described as an E-cadherin-associated protein; and has been shown to associate with other members of the cadherin family; such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin; which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin has also been found in complexes with the tumor suppressor protein APC.
Host:
Mouse
Immunogen:
Recombinant chicken β-catenin
Isotype:
IgG1
Molecular Weight:
92kDa
Research Area:
Apoptosis; Autophagy; BBB VCAM-1 Signaling; Basal Cell Marker; Breast Cancer; Cancer; Cardiovascular; Colon Cancer; Developmental Biology; Immunology; Infectious Disease; Signal Transduction; Transcri
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody