CTBP2 (C-terminal binding protein 2) Antibody
Product Sizes
100 ug
£671.00
1488-MSM1-P1-100UG
About this Product
- SKU:
- 1488-MSM1-P1
- Application:
- Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- PCRP-CTBP2-1A9
- Clonality:
- Monoclonal
- Extra Details:
- The gene CTBP2 (C-terminal binding protein 2) encodes a member of the CtBP-family. The gene is mapped to human chromosome 21q21.3. It is found to be expressed ubiquitously; with higher expression in the heart; skeletal muscle; and pancreas. The gene CTBP2 (C-terminal binding protein 2) encodes a protein that functions as a transcriptional co-repressor of several tumor suppressor genes resulting in enhanced cancer cell migration and invasion. Its expression is found to be upregulated in hepatocellular carcinoma (HCC). It may be a potential prognostic marker for post liver resection HCC. It is involved in several types of tumor initiation; progression and response to therapy. It is found to interact with the C-terminal region of adenovirus type 2/5 E1A protein; a region that negatively regulates tumorigenicity and the extent of oncogenic transformation.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human CTBP2 protein
- Isotype:
- IgG2b
- Molecular Weight:
- 95.2kDa
- Research Area:
- Cardiovascular; Infectious Disease; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=112623
