Recombinant Neuronal-Nuclei (NeuN) (Neuronal Marker) Antibody
Product Sizes
100 ug
£671.00
146713-RBM1-P1ABX-100UG
About this Product
- SKU:
- 146713-RBM1-P1ABX
- Additional Names:
- Fox-1 homolog C | Neuronal nuclei antigen
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- NeuN/288R
- Clonality:
- Monoclonal
- Extra Details:
- NeuN antibody specifically recognizes the DNA-binding; neuron-specific protein NeuN; which is present in most CNS and PNS neuronal cell types of all vertebrates tested. NeuN protein distributions are apparently restricted to neuronal nuclei and some proximal neuronal processes in both fetal and adult brain although; some neurons fail to be recognized by NeuN at all ages: INL retinal cells; Cajal-Retzius cells; Purkinje cells; inferior olivary and dentate nucleus neurons; and sympathetic ganglion cells are examples. Immunohistochemically detectable NeuN protein first appears at developmental timepoints that correspond with the withdrawal of the neuron from the cell cycle and/or with the initiation of terminal differentiation of the neuro. Immunoreactivity appears around E9.5 in the mouse neural tube and is extensive throughout the developing nervous system by E12.5. Strong nuclear staining suggests a nuclear regulatory protein function; however; no evidence currently exists as to whether the NeuN protein antigen has a function in the distal cytoplasm or whether it is merely synthesized there before being transported back into the nucleus. No difference between protein isolated from purified nuclei and whole brain extract on immunoblots has been found.
- Host:
- Rabbit
- Immunogen:
- Recombinant full-length human NeuN protein
- Isotype:
- IgG
- Molecular Weight:
- 48kDa
- Research Area:
- Neuroscience; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=112593
