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Antibodies

ZBTB46 / BTBD4 / ZNF340 Antibody

Product Sizes
100 ug
£671.00
140685-MSM1-P1-100UG
About this Product
SKU:
140685-MSM1-P1
Additional Names:
BTB-ZF protein expressed in effector lymphocytes | BTB/POZ domain-containing protein 4 | Zinc finger protein 340
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
translate.label.attr.clone:
PCRP-ZBTB46-2B8
Clonality:
Monoclonal
Extra Details:
BTBD4 (BTB/POZ domain-containing protein 4); also known as zinc finger protein 340 (ZNF340) or zinc finger and BTB domain-containing protein 46 (ZBTB46); is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ inter- actions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins; including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein; this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted; as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias; this tran- scriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.
Host:
Mouse
Immunogen:
Recombinant full-length human ZBTB46 protein
Isotype:
IgG2a
Molecular Weight:
64kDa
Research Area:
Dendritic Cell Marker; Nuclear Marker
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody