ZBTB46 / BTBD4 / ZNF340 Antibody
Product Sizes
20 ug
£364.00
140685-MSM1-P0-20UG
About this Product
- SKU:
- 140685-MSM1-P0
- Additional Names:
- BTB-ZF protein expressed in effector lymphocytes | BTB/POZ domain-containing protein 4 | Zinc finger protein 340
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- PCRP-ZBTB46-2B8
- Clonality:
- Monoclonal
- Extra Details:
- BTBD4 (BTB/POZ domain-containing protein 4); also known as zinc finger protein 340 (ZNF340) or zinc finger and BTB domain-containing protein 46 (ZBTB46); is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ inter- actions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins; including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein; this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted; as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias; this tran- scriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human ZBTB46 protein
- Isotype:
- IgG2a
- Molecular Weight:
- 64kDa
- Research Area:
- Dendritic Cell Marker; Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=112536
