ATF2 Antibody
Product Sizes
20 ug
£364.00
1386-MSM2-P0-20UG
About this Product
- SKU:
- 1386-MSM2-P0
- Additional Names:
- Activating transcription factor 2 | Cyclic AMP-responsive element-binding protein 2 | HB16 | cAMP response element-binding protein CRE-BP1
- Application:
- Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- PCRP-ATF2-1B4
- Clonality:
- Monoclonal
- Extra Details:
- This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE); an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human ATF2 protein
- Isotype:
- IgG2b
- Molecular Weight:
- 54.5kDa
- Research Area:
- Cardiovascular; Cytokine Signaling; Immunology; MAPK Signaling; Nuclear Marker; Signal Transduction; Stem Cell Differentiation; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=112534
