CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Antibody
Product Sizes
100 ug
£671.00
1380-MSM4-P1-100UG
About this Product
- SKU:
- 1380-MSM4-P1
- Additional Names:
- Complement C3d receptor | Epstein-Barr virus receptor
- Application:
- ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- CR2/2754
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 140kDa; which is identified as the complement receptor 2 (CR2) or CD21. This protein is expressed strongly on mature B cells; follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny; CD21 appears after the pre-B-stage; is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d; C3dg and iC3b Complement components; for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19; CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 142-240) of human CR2 (CD21) protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 140kDa
- Research Area:
- B Cell Markers; Complement System; Dendritic Cell Marker; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=112507
