Recombinant CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Antibody

Product Sizes

20 ug

£364.00

1380-MSM22-P0-20UG

About this Product

SKU:: 1380-MSM22-P0
Additional Names:: Complement C3d receptor | Epstein-Barr virus receptor
Application:: Immunohistochemistry
translate.label.attr.clone:: rCR2/9537
Clonality:: Monoclonal
Extra Details:: Recognizes a protein of 140kDa; which is identified as the complement receptor 2(CR2)/CD21. This protein is expressed strongly on mature B cells; follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny; CD21 appears after the pre-B-stage; is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro.CD21 functions as receptor for C3d; C3dg and iC3b Complement components; for EBV and for IFNalpha.CD21 binds to CD23 and associates with CD19; CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.
Host:: Mouse
Immunogen:: Recombinant fragment (around aa 100-300) of human CR2 (CD21) protein (exact sequence is proprietary)
Isotype:: IgG2b
Molecular Weight:: 140kDa
Research Area:: B Cell Markers; Complement System; Dendritic Cell Marker; Immunology
Shipping Conditions:: Blue Ice
Storage Conditions:: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:: NeoBiotechnologies
Type:: Antibodies: Monoclonal Antibody

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