CD35 / CR1 (Follicular Dendritic Cell Marker) Antibody

Product Sizes

100 ug

£671.00

1378-MSM1X-P1ABX-100UG

About this Product

SKU:: 1378-MSM1X-P1ABX
Additional Names:: C3b/C4b receptor
Application:: Flow Cytometry, Immunofluorescence, Immunohistochemistry
translate.label.attr.clone:: SPM554
Clonality:: Monoclonal
Extra Details:: Recognizes a protein of 210-220kDa; which is identified as the complement receptor 1 (CR1)/CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site; so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b; the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein.Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.
Host:: Mouse
Immunogen:: Intact human monocytes
Isotype:: IgG1
Molecular Weight:: 210-220kDa
Research Area:: Complement System; Immunology; Transcription Factors
Shipping Conditions:: Blue Ice
Storage Conditions:: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:: NeoBiotechnologies
Type:: Antibodies: Monoclonal Antibody

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