Carboxypeptidase A1 / CPA1 (Pancreatic Cancer Marker) Antibody

Product Sizes

100 ug

£671.00

1357-MSM23-P1ABX-100UG

About this Product

SKU:: 1357-MSM23-P1ABX
Application:: Immunohistochemistry
translate.label.attr.clone:: CPA1/8784
Clonality:: Monoclonal
Extra Details:: Human pancreatic procarboxypeptidase A exists as three different active forms; two of which are designated carboxypeptidase A1 (CPA1) and carboxypeptidase A2 (CPA2). CPA1; also known as CPA; is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase; CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins; thereby playing a key role in protein digestion and degradation. Via its catalytic activity; CPA1 is also thought to be involved in zymogen (proenzyme) inhibition; probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer; suggesting a possible role in either tumor progression or tumor suppression events.
Host:: Mouse
Immunogen:: Recombinant full-length human CPA1 protein
Isotype:: IgG2a
Molecular Weight:: 47kDa
Research Area:: Mast Cell Marker
Shipping Conditions:: Blue Ice
Storage Conditions:: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:: NeoBiotechnologies
Type:: Antibodies: Monoclonal Antibody

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