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Antibodies

Recombinant Collagen II (COL2A1) Antibody

Product Sizes
100 ug
£671.00
1280-RBM4-P1-100UG
About this Product
SKU:
1280-RBM4-P1
Additional Names:
Alpha-1 type II collagen
Application:
Immunohistochemistry
translate.label.attr.clone:
COL2A1/8810R
Clonality:
Monoclonal
Extra Details:
The extensive family of COL gene products (collagens) is composed of several chain types; including fibril-forming interstitial collagens (types I; II; III and V) and basement membrane collagens (type IV); each type containing multiple isoforms. Collagens are fibrous; extracellular matrix proteins with high tensile strength and are the major components of connective tissue; such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion; important for maintaining normal tissue architecture and function. In cartilage; Collagen Type II constitutes the bulk of the fibril. Sensitization with Collagen Type II induces an erosive polyarthritis in rats; mice and higher primates which can resemble rheumatoid arthritis and relapsing polychrondritis.
Host:
Rabbit
Immunogen:
bovine collagen type II (CII).
Isotype:
IgG
Molecular Weight:
190kDa
Research Area:
Articular Cartilage Extracellular Matrix; Cardiovascular; Developmental Biology; Immunology; Mesenchymal Stem Cell Differentiation; Nuclear Marker; Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody