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Antibodies

Recombinant Calponin-1 (Smooth Muscle Marker) Antibody

Product Sizes
100 ug
£671.00
1264-RBM4-P1-100UG
About this Product
SKU:
1264-RBM4-P1
Additional Names:
Basic calponin | Calponin H1; smooth muscle
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
translate.label.attr.clone:
CNN1/1408R
Clonality:
Monoclonal
Extra Details:
Multiple isoelectric variants of calponin have been identified; however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form; I-calponin; is primarily restricted to muscle of the urogenital tract; whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting; this MAb reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin; F-actin and tropomyosin binding protein; which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
Host:
Rabbit
Immunogen:
Recombinant human full-length CNN1 protein
Isotype:
IgG
Molecular Weight:
34kDa
Research Area:
Cardiovascular; Mesenchymal Stem Cell Differentiation
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody