Recombinant Calponin-1 (Smooth Muscle Marker) Antibody
Product Sizes
20 ug
£364.00
1264-MSM8-P0-20UG
About this Product
- SKU:
- 1264-MSM8-P0
- Additional Names:
- Basic calponin | Calponin H1; smooth muscle
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- rCNN1/6918
- Clonality:
- Monoclonal
- Extra Details:
- Multiple isoelectric variants of calponin have been identified; however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form; I-calponin; is primarily restricted to muscle of the urogenital tract; whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting; this MAb reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin; F-actin and tropomyosin binding protein; which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa197-297) of human CNN1 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 34kDa
- Research Area:
- Cardiovascular; Mesenchymal Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=127821
