Alpha-1-Antichymotrypsin (SERPINA3) (Histiocytoma Marker) Antibody
Product Sizes
20 ug
£364.00
12-MSM13-P0-20UG
About this Product
- SKU:
- 12-MSM13-P0
- Additional Names:
- Cell growth-inhibiting gene 24/25 protein | Serpin A3
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- AACT/1451 + AACT/1452
- Clonality:
- Monoclonal
- Extra Details:
- It recognizes a protein of 65-76kDa; which is identified antichymotrypsin (AACT). AACT is a plasma protease inhibitor synthesized in the liver as a single glycopeptide chain. In human; the normal serum level of AACT is about one-tenth that of 伪 1-antitrypsin (AAT); with which it shares nucleic acid and protein sequence homology. Both are major acute phase reactants; their concentrations in plasma increase in response to trauma; surgery and infection. Elevated levels of AACT are widely; but not universally; reported in the cerebrospinal fluid and plasma of AD patients. Prostate-specific antigen (PSA) and its SDS-stable complex with AACT are in widespread use as markers for the diagnosis of prostate cancer. AACT deficiency may also be a possible cause of chronic liver disease. AACTantibody reacts with histiocytes and histiocytic neoplasms. It is widely used to identify histiocytes and tumors derived from them. Acinar tumors of the pancreas and salivary gland may also exhibit AACT positivity.
- Host:
- Mouse
- Immunogen:
- Recombinant human Antichymotrypsin (AACT) protein fragment (around aa 49-187) (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 65-76kDa
- Research Area:
- Cardiovascular; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=112320
