Recombinant Clusterin / Apolipoprotein J (APO-J) (Marker of Anaplastic Large Cell Lymphoma) Antibody
Product Sizes
100 ug
£671.00
1191-MSM46-P1ABX-100UG
About this Product
- SKU:
- 1191-MSM46-P1ABX
- Additional Names:
- Aging-associated gene 4 protein | Apolipoprotein J | Complement cytolysis inhibitor | Complement-associated protein SP-40; 40 | Ku70-binding protein 1 | NA1/NA2 | Sulfated glycoprotein 2 | Testosterone-repressed prostate message 2 | ApoJalpha | Complement cytolysis inhibitor a chain | SP-40; 40 beta-chain | ApoJbeta | Complement cytolysis inhibitor b chain | SP-40; 40 alpha-chain
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- r7D1
- Clonality:
- Monoclonal
- Extra Details:
- Clusterin; also known as apolipoprotein J (ApoJ); complement lysis inhibitor (CLI); gp80; glycoprotein III; sulfated glycoprotein 2 (SGP2); SP40-40; testosterone-repressed prostate message 2 (TRPM2); and T64; is a secretory; heterodimeric glycoprotein of approximately 80 kD composed of two disulfide-linked subunits; alpha (residues 228–449) and beta (residues 23–227). It is synthesized as a 449-amino acid polypeptide and post-translationally cleaved at an internal bond between Arg 227 and Ser 228. Clusterin interacts with a broad range of molecules and plays a role in diverse biological processes; including immune regulation; lipid transport; sperm maturation; complement cascade regulation; membrane recycling; cell adhesion; morphological transformation; tissue remodeling; and cell-cell interactions. It also influences β-amyloid structure and neuritic toxicity in vivo; suggesting a potential role in Alzheimer’s disease pathogenesis. Notably; Clusterin overexpression is more common in the late stages of mammary tumor progression.
- Host:
- Mouse
- Immunogen:
- Prokaryotic recombinant protein corresponding to a portion of the alpha subunit of the human clusterin molecule.
- Isotype:
- IgG1
- Molecular Weight:
- 70kDa (precursor); 36-39kDa (alpha); 34-36kDa (beta)
- Research Area:
- Cardiovascular; Complement System; Immunology; Neuroscience
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=141325
