Recombinant Topoisomerase I; Mitochondrial (TOP1MT) Antibody
Product Sizes
100 ug
£671.00
116447-RBM4-P1-100UG
About this Product
- SKU:
- 116447-RBM4-P1
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- TOP1MT/2883R
- Clonality:
- Monoclonal
- Extra Details:
- DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication; recombination; and transcription; DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I; mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase; mitochondrial Topo I requires a divalent metal; either; calcium or magnesium; as well as an alkaline pH for optimal activity.
- Host:
- Rabbit
- Immunogen:
- Recombinant full-length human TOP1MT protein
- Isotype:
- IgG
- Molecular Weight:
- 70kDa
- Research Area:
- Cardiovascular; Mitochondria Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=112260
