IL22RA2 Antibody
Product Sizes
100 ug
£671.00
116379-MSM1-P1ABX-100UG
About this Product
- SKU:
- 116379-MSM1-P1ABX
- Additional Names:
- Cytokine receptor class-II member 10 | Cytokine receptor family 2 member 10 | Cytokine receptor family type 2; soluble 1 | Interleukin-22-binding protein | ZcytoR16
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- IL22RA2/7291
- Clonality:
- Monoclonal
- Extra Details:
- IL-22Rα2 (Interleukin-22 receptor α2 chain); also known as IL-22 binding protein (IL-22BP); cytokine receptor family class II member 10 (CRF2-10) or CRF2- soluble 1 (CRF2-S1); is a soluble; nonsignaling single chain receptor for IL-22. It is highly expressed in intestine and lymph nodes and is also found in spleen; kidney and liver. IL-22Rα2 has a cytokine-binding domain that contains two FnIII domains. Its affinity for IL-22 is 4- to 10-fold higher than that of the membrane-bound IL-22 receptor; however it has a dissociation rate up to 20 times lower. By binding to IL-22; IL-22Rα2 prevents the binding to the IL-22 membrane-bound receptor and therefore inhibits IL-22 signaling. This suggests that IL-22Rα2 may be important in regulating inflammatory responses. In addition; IL-22Rα2 can be induced by lipopolysaccharides (LPSs).
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa1-200) of human IL22RA2 protein (exact sequence is proprietary)
- Isotype:
- IgG2
- Molecular Weight:
- 27 kDa
- Research Area:
- Cardiovascular; Cytokine Signaling; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=131358
