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Antibodies

Creatine Kinase MM Antibody

Product Sizes
20 ug
£364.00
1158-MSM1-P0-20UG
About this Product
SKU:
1158-MSM1-P0
Additional Names:
Creatine kinase M chain | Creatine phosphokinase M-type | M-CK
Application:
ELISA, Western Blot
translate.label.attr.clone:
CKMM/3341
Clonality:
Monoclonal
Extra Details:
T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen; followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that; when engaged; potentiates T cell expansion in a CD28-independent manner. B7; also designated BB1; is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.
Host:
Mouse
Immunogen:
Recombinant full-length CKM protein
Isotype:
IgG2a
Molecular Weight:
43kDa
Research Area:
Cardiovascular
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody