BTBD9 Antibody
Product Sizes
100 ug
£671.00
114781-MSM1-P1-100UG
About this Product
- SKU:
- 114781-MSM1-P1
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- BTBD9/7501
- Clonality:
- Monoclonal
- Extra Details:
- BTBD9 (BTB/POZ domain-containing protein 9) is a 612 amino acid protein that contains one BTB/POZ domain and one BACK (BTB/Kelch associated) domain. The BTB/POZ domain mediates homomeric and heteromeric POZPOZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins; including Bcl-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein; this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted; as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias; this transcriptional repression is attenuated. This suggests that BTBD9 may play a role in transcription regulation. Genetic variations in the gene that encodes BTBD9 have been associated with susceptibility to restless legs syndrome type 6 (RLS6); a condition characterized by an uncontrollable urge to move the legs while resting.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa200-400) of human BTBD9 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 69kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=132427
