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Antibodies

GPN1 / XAB1 (DNA Repair & Protein Synthesis) Antibody

Product Sizes
100 ug
£671.00
11321-MSM1-P1ABX-100UG
About this Product
SKU:
11321-MSM1-P1ABX
Additional Names:
MBD2-interacting protein (MBDin) | RNAPII-associated protein 4 | XPA-binding protein 1
Application:
ELISA, Western Blot
translate.label.attr.clone:
GPN1/2350
Clonality:
Monoclonal
Extra Details:
GPN1 is involved in protein synthesis events. It is expressed ubiquitously with highest expression in testis. It binds to the RNA polymerase II- (Poll II) associated proteins RPAP1-3 and to XPA (a protein involved in DNA repair mechanisms); thereby forming an interface with Poll II. Via this interaction; GPN1 is thought to mediate the involvement of Pol II in both protein complex formation and protein chaperone/ scaffolding activities. In addition; GPN1 interacts with components of the integrator and molecular chaperone complexes; further implicating GPN1 in protein assembly. GPN1 contains a cluster of acidic amino acids in its C-terminal region and a series of sequences similar to those found in GTP-binding proteins in its N-terminal region; suggesting that GPN1 has possible GTPase activity.
Host:
Mouse
Immunogen:
Recombinant full-length human GPN1 protein
Isotype:
IgG1
Molecular Weight:
42kDa
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody