ECD/ SGT1 Antibody
Product Sizes
100 ug
£671.00
11319-MSM1-P1-100UG
About this Product
- SKU:
- 11319-MSM1-P1
- Additional Names:
- Human suppressor of GCR two
- Application:
- Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- PCRP-ECD-1D10
- Clonality:
- Monoclonal
- Extra Details:
- Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes. Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins. The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex. May play a role in regulation of pre-mRNA splicing.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human ECD protein
- Isotype:
- IgG2b
- Molecular Weight:
- 72.76kDa
- Research Area:
- Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=112201
