NACC1 / Nac1 / BTBD14B Antibody
Product Sizes
100 ug
£671.00
112939-MSM2-P1ABX-100UG
About this Product
- SKU:
- 112939-MSM2-P1ABX
- Additional Names:
- BTB/POZ domain-containing protein 14B
- Application:
- Flow Cytometry
- translate.label.attr.clone:
- PCRP-NACC1-1A8
- Clonality:
- Monoclonal
- Extra Details:
- The BTB (broad-complex; tramtrack and bric a brac) domain; also known as the POZ (poxvirus and zinc finger) domain; is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD14B (BTB/POZ domain-containing protein 14B); also known as NACC1 (nucleus accumbens associated 1); BEND8 or NAC1; is a 527 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BTB (POZ) domain. Existing as a homo-oligomer that interacts with HDAC3 and HDAC4; BTBD14B functions as a transcriptional repressor that influences the transcriptional activity of CRIF1 and is required for proteasome recruitment to the nucleus and cytoplasm in dendritic spines. BTBD14B is overexpressed in multiple carcinomas; suggesting a role in tumor development and metastasis.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human NACC1 protein
- Isotype:
- IgG2a
- Molecular Weight:
- 57kDa
- Research Area:
- Neuroscience; Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=112200
