Ubiquitin-conjugating Enzyme E2C / UBCH10 Antibody
Product Sizes
100 ug
£671.00
11065-MSM1-P1ABX-100UG
About this Product
- SKU:
- 11065-MSM1-P1ABX
- Additional Names:
- (E3-independent) E2 ubiquitin-conjugating enzyme C | E2 ubiquitin-conjugating enzyme C | UbcH10 | Ubiquitin carrier protein C | Ubiquitin-protein ligase C
- Application:
- ELISA, Immunohistochemistry
- translate.label.attr.clone:
- CPTC-UBE2C-1
- Clonality:
- Monoclonal
- Extra Details:
- The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ubconjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2C; also designated UBCH10 in human; is an E2 ubiquitin conjugating enzyme for the anaphase promoting complex (APC); which coordinates mitosis and G1 by sequentially promoting the degradation of key cell-cycle regulators. UBE2C is overexpressed in many different types of cancers and may be a potential therapeutic target.
- Host:
- Mouse
- Immunogen:
- Recombinant human full-length UBE2C protein
- Isotype:
- IgG2b
- Molecular Weight:
- 20kDa
- Research Area:
- Immunology; Infectious Disease; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=112057
