Recombinant Choline Acetyltransferase (CHAT) (Marker of Cholinergic Cells) Antibody
Product Sizes
100 ug
£671.00
1103-MSM6-P1ABX-100UG
About this Product
- SKU:
- 1103-MSM6-P1ABX
- Additional Names:
- Choline acetyltransferase | CHOACTase | ChAT
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- r38B12
- Clonality:
- Monoclonal
- Extra Details:
- Choline acetyltransferase (ChAT) is a 68 kD enzyme which catalyses the synthesis of acetylcholine (Ach) from choline and acetyl coenzyme A. The human ChAT gene encodes two proteins; the 68 kD ChAT enzyme and a 27 kD protein immunologically related and coexpressed with ChAT in cholinergic neurons of the central nervous system. The smaller proteins may play a role in the regulation of ACh synthesis. ChAT is expressed in cholinergic neurons; the majority of the neurons in the nucleus basalis of Meynert; large neurones in the striatum (putamen and caudate nuclei); the majority of neurones in the pedunculo-pontine; hypoglossal; dorsal nucleus of vagus and subgroups of neurones in Roller’s and the medial olivary accessory nuclei. Prominent staining is observed in ribonucleoprotein; distributed at the periphery of large neurons of the nucleus basalis of Meynert; the motor neurons in the hypoglossal and ambiguus nuclei. NCL-ChAT does not label axons in the insular cortex of the internal capsule non-cholinergic structures; endothelial cells or microglia.
- Host:
- Mouse
- Immunogen:
- Prokaryotic recombinant protein corresponding to the C-terminal region of the human ChAT molecule.
- Isotype:
- IgG1
- Molecular Weight:
- 82kDa
- Research Area:
- Metabolism; Neuroscience
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=145774
