Recombinant MALT1 (MALT-Lymphoma Marker) Antibody
Product Sizes
100 ug
£671.00
10892-RBM2-P1ABX-100UG
About this Product
- SKU:
- 10892-RBM2-P1ABX
- Additional Names:
- MALT lymphoma-associated translocation | Paracaspase
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- MT1/3159R
- Clonality:
- Monoclonal
- Extra Details:
- Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene; which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene; which maps to human chromosome 18q21; and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10; which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells; mature B cells and plasma cells.
- Host:
- Rabbit
- Immunogen:
- Human MALT1 recombinant fragment (aa701-808)
- Isotype:
- IgG
- Molecular Weight:
- 93kDa
- Research Area:
- Apoptosis; Autophagy; Cardiovascular; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=112027
