LILRB1 / ILT-2 / CD85j Antibody
Product Sizes
100 ug
£671.00
10859-MSM1-P1-100UG
About this Product
- SKU:
- 10859-MSM1-P1
- Additional Names:
- CD85 antigen-like family member J | Immunoglobulin-like transcript 2 | Monocyte/macrophage immunoglobulin-like receptor 7
- Application:
- Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- VMP55
- Clonality:
- Monoclonal
- Extra Details:
- Leukocyte immunoglobulin-like receptors (LIRs) are members of the immunoglobulin superfamily of glycoproteins and are predominantly expressed by monocytes; B cells; dendritic cells; natural killer (NK) cells; peripheral blood leukocytes and tissues such as placenta; lung and liver. Immunoglobulin-like transcript 2 (ILT-2); also known as CD85 or MIR7; is a 650 amino acid glycoprotein that contains a 23 amino acid signal peptide; 4 extracellular C2-type IGSF domains and 4 intracellular ITIM motifs. ILT-2 can bind major histocompatability (MHC) class I molecules and inhibit cell termination by natural killer (NK) and T cells; and inhibit Ca2+ mobilization in myeloid cells triggered through the B cell antigen receptor and histocompatibility leukocyte antigens (HLA)-DR. ILT-2 contains four putative cytoplasmic tyrosine-based inhibitory motifs and upon tyrosine phosphorylation; associates with the tyrosine phosphatase SHP-1.
- Host:
- Mouse
- Immunogen:
- Hairy cell leukemia cells
- Isotype:
- IgG1
- Molecular Weight:
- 110/90kDa
- Research Area:
- Cardiovascular; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=112023
