ALDH1L1 Antibody
Product Sizes
100 ug
£671.00
10840-MSM1-P1-100UG
About this Product
- SKU:
- 10840-MSM1-P1
- Additional Names:
- Aldehyde dehydrogenase family 1 member L1
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- ALDH1L1/7701
- Clonality:
- Monoclonal
- Extra Details:
- Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde; lipid peroxidation and metabolism of corticosteroids; biogenic amines and neurotransmitters. ALDH1L1 (aldehyde dehydrogenase 1 family member L1); also known as FTHFD or 10-FTHFD (10-formyltetrahydrofolate dehydrogenase); is a cytosolic protein that is developmentally regulated in the cerebellum. ALDH1L1 binds to folate and catalyzes the conversion of 10-formyltetrahydrofolate (10-FTHF) to tetrahydrofolate (THF). This suggests a possible role for ALDH1L1 in the regulation of cellular THF levels as well as in the inhibition of cell proliferation (as 10-FTHF is essential for the synthesis of purine). In addition; the overexpression of ALDH1L1 can restrict cell proliferation in vitro.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa400-600) of human ALDH1L1 protein (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 99kDa
- Research Area:
- Cardiovascular
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=132454
