HCG-beta (Pregnancy & Choriocarcinoma Marker) Antibody

Product Sizes

100 ug

£671.00

1082-MSM1-P1ABX-100UG

About this Product

SKU:: 1082-MSM1-P1ABX
Application:: Immunohistochemistry
translate.label.attr.clone:: HCGb/54
Clonality:: Monoclonal
Extra Details:: This MAb reacts with a protein of 22kDa; identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein; which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical; non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH); and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.
Host:: Mouse
Immunogen:: Recombinant full-length hCG beta protein
Isotype:: IgG1
Molecular Weight:: 22kDa
Research Area:: Transcription Factors
Shipping Conditions:: Blue Ice
Storage Conditions:: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:: NeoBiotechnologies
Type:: Antibodies: Monoclonal Antibody

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