Recombinant CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Antibody
Product Sizes
100 ug
£671.00
1080-RBM20-P1ABX-100UG
About this Product
- SKU:
- 1080-RBM20-P1ABX
- Additional Names:
- ATP-binding cassette sub-family C member 7 | Channel conductance-controlling ATPase | cAMP-dependent chloride channel
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- CFTR/9148R
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 165-170kDa; identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD); two nucleotide-binding domains (NBD); and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters; also known as traffic ATPases; which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3';5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas; airway; intestine; bile duct; sweat gland; and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa 258-385) of human CFTR protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 165-170kDa
- Research Area:
- Cardiovascular; Infectious Disease; Signal Transduction; Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=128080
