CFL2 / NEM7 Antibody
Product Sizes
20 ug
£364.00
1073-MSM3-P0-20UG
About this Product
- SKU:
- 1073-MSM3-P0
- Additional Names:
- CFL 2 antibody; CFL2 antibody; COF2_HUMAN antibody; Cofilin 2 muscle antibody; Cofilin antibody; Cofilin muscle antibody; Cofilin muscle isoform antibody; Cofilin-2 antibody; Cofilin2 antibody; muscle isoform antibody; NEM 7 antibody; NEM7 antibody
- translate.label.attr.clone:
- CFL2/9963
- Clonality:
- Monoclonal
- Extra Details:
- Cofilin is ubiquitously expressed in eukaryotic cells where it binds to Actin; thereby regulating the rapid cycling of Actin assembly and disassembly essential for cellular viability. Cofilin is a low molecular weight protein that binds to filamentous (F) Actin by bridging two longitudinally associated Actin subunits changing the F-Actin filament twist. This process is allowed by the dephosphorylation of Cofilin Ser-3 by factors such as opsonized zymosan. Lim kinase 1; a serine kinase; phosphorylates Cofilin and renders it unable to bind and depolymerise F-Actin.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa1-166) of human CFL2 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 19-21kDa
- Research Area:
- Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=139310
