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Antibodies

CETN1 / Centrin-1 Antibody

Product Sizes
20 ug
£364.00
1068-MSM7-P0-20UG
About this Product
SKU:
1068-MSM7-P0
Additional Names:
Caltractin antibody Caltractin isoform 2 antibody; CEN 1 antibody; CEN1 antibody; Centrin EF hand protein 1 antibody; Centrin-1 antibody; Centrin1 antibody; CETN 1 antibody; CETN antibody; CETN1 antibody; CETN1_HUMAN antibody; EF hand protein 1 antibody
Application:
Immunohistochemistry, Western Blot
translate.label.attr.clone:
CETN1/9877
Clonality:
Monoclonal
Extra Details:
Centrin-1 Antibody (2A6) is an IgG1 κ mouse monoclonal Centrin-1 antibody (also designated Caltractin isoform 2 antibody or CETN1 antibody) that detects the Centrin-1 protein of human origin by WB; IP and ELISA. Centrin-1 Antibody (2A6) is available as the non-conjugated anti-Centrin-1 antibody. EF-hand type Ca2+-binding proteins consists of several family members; including Centrin-1; Centrin-2 and Centrin-3. The Centrin proteins are ubiquitously expressed cytoskeletal components that show increased expression during cell differentiation. Tissues where cilia are present; such as the retina and testis; express both Centrin-1 and -2; but Centrin-2 is also expressed in nondifferentiated; nonciliated retinal cells (retinoblastoma cells); liver; skeletal muscle; and cardiac muscle. In these tissues; Centrin associates with the centrosomes; mitotic spindle poles; and basal bodies. Knockdown studies reveal a requirement for Centrin in centriole duplication and organization of spindle pole morphology and the completion of cytokinesis. Centrin-3 plays a role in centrosome reproduction.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa1-172) of human CETN1 protein (exact sequence is proprietary)
Isotype:
IgG
Molecular Weight:
20KDa
Research Area:
Cardiovascular; Complement System; Immunology; Neuroscience
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody