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Antibodies

CETN1 / Centrin-1 Antibody

Product Sizes
100 ug
£671.00
1068-MSM10-P1-100UG
About this Product
SKU:
1068-MSM10-P1
Additional Names:
Caltractin; Caltractin isoform 2; CEN 1; CEN1; Centrin EF hand protein 1; Centrin-1; Centrin1; CETN 1; CETN; CETN1; CETN1_HUMAN; EF hand protein 1
Application:
Immunohistochemistry
translate.label.attr.clone:
CETN1/9880
Clonality:
Monoclonal
Extra Details:
EF-hand type Ca2+-binding proteins consists of several family members; including Centrin-1; Centrin-2 and Centrin-3. The Centrin proteins are ubiquitously expressed cytoskeletal components that show increased expression during cell differentiation. Tissues where cilia are present; such as the retina and testis; express both Centrin-1 and -2; but Centrin-2 is also expressed in nondifferentiated; nonciliated retinal cells (retinoblastoma cells); liver; skeletal muscle; and cardiac muscle. In these tissues; Centrin associates with the centrosomes; mitotic spindle poles; and basal bodies. Knockdown studies reveal a requirement for Centrin in centriole duplication and organization of spindle pole morphology and the completion of cytokinesis. Centrin-3 plays a role in centrosome reproduction.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa 1-172) of human CETN1 protein (exact sequence is proprietary)
Isotype:
IgG
Molecular Weight:
20KDa
Research Area:
Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody