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Antibodies

DMRT2 (Transcription Factor) Antibody

Product Sizes
100 ug
£671.00
10655-MSM1-P1-100UG
About this Product
SKU:
10655-MSM1-P1
Additional Names:
Doublesex-like 2 protein
Application:
Flow Cytometry, Western Blot
translate.label.attr.clone:
PCRP-DMRT2-1B11
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene belongs to the DMRT gene family; sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3; genes involved in sex determination in these organisms. Also; this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome; dermomyotome and myotome (By similarity).
Host:
Mouse
Immunogen:
Recombinant full-length human DMRT2 protein
Isotype:
IgG2b
Molecular Weight:
62kDa
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody