Recombinant Periostin (POSTN) Antibody
Product Sizes
20 ug
£364.00
10631-RBM13-P0-20UG
About this Product
- SKU:
- 10631-RBM13-P0
- Additional Names:
- Osteoblast-specific factor 2
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- POSTN/8951R
- Clonality:
- Monoclonal
- Extra Details:
- Periostin (PN); also designated osteoblast-specific factor 2 (OSF-2); is a disulfide linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for αVβ3 and αVβ5 integrins. In preosteoblasts; Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment; spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract; aorta; stomach; placenta; uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor β 1 (TGF β 1). Periostin contains a typical signal sequence; followed by a cysteine-rich domain; a fourfold repeated domain; which shows homology with the insect protein fasciclin; and a C-terminal domain.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment of human POSTN protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 84/74kDa (Periostin); 90kDa (secreted glycoprotein)
- Research Area:
- Cardiovascular; Endothelial Cell Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=134806
