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Antibodies

Recombinant Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker) Antibody

Product Sizes
20 ug
£364.00
10630-RBM2-P0-20UG
About this Product
SKU:
10630-RBM2-P0
Additional Names:
Aggrus | Glycoprotein 36 | PA2.26 antigen | T1-alpha
Application:
ELISA, Immunofluorescence, Western Blot
translate.label.attr.clone:
PDPN/4009R
Clonality:
Monoclonal
Extra Details:
It recognizes a muco-protein of 38-43kDa; which is identified as Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium; podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endotheliumas well as lymphoangiomas;Kaposi sarcomas;and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore; it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.
Host:
Rabbit
Immunogen:
Synthetic peptide corresponding to residues within aa1-100 of Podoplanin
Isotype:
IgG
Molecular Weight:
17kDa
Research Area:
Angiogenesis; Dendritic Cell Marker; Endothelial Cell Marker
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody