DRAP1 / NC2 alpha Antibody
Product Sizes
20 ug
£364.00
10589-MSM1-P0-20UG
About this Product
- SKU:
- 10589-MSM1-P0
- Additional Names:
- Dr1-associated protein 1 | Negative cofactor 2-alpha
- Application:
- Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- PCRP-DRAP1-1A12
- Clonality:
- Monoclonal
- Extra Details:
- NC2 (negative cofactor 2) is a dimeric histone-fold complex that represses RNA polymerase II transcription through binding to TBP and inhibiting the transcription factors TFIIA and TFIIB. NC2 consists of two subunits; termed NC2a and NC2β; and these subunits dimerize and bind to TBP-promoter complexes via histone fold domains of the H2A-H2B type. NC2 associates with promoters in a manner that correlates with transcriptional activity and with occupancy by basal transcription factors. NC2 binds directly to DNA; and the binding of NC2 to TBP-promoter complexes affects the conformation of DNA; and results in the inhibition of TFIIB.
- Host:
- Mouse
- Immunogen:
- Recombinant human DRAP1 protein
- Isotype:
- IgG2b
- Molecular Weight:
- 22.35Da
- Research Area:
- Developmental Biology; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=127465
